Cancer Genomics & Molecular Profiling
Identifying differentially expressed genes, mutations, and molecular alterations in cervical, breast, gastric, and gallbladder cancers using GEO and TCGA datasets.
Cancer Genomics
& Therapeutics Lab
Decoding the molecular basis of cancer through genomic profiling, computational analysis, and targeted therapeutic development across cervical, breast, gastric, and gallbladder cancers. A research laboratory at Mahatma Gandhi Central University, Motihari, Bihar.
Supported by
Government of Bihar
Bihar Council on Science & Technology
Mahatma Gandhi Central University
Motihari, Bihar
Our Research
Pioneering Cancer Research
Our research spans from identifying differentially expressed genes in tumours to developing targeted drug delivery systems — grounded in real data from GEO, TCGA, and clinical cohorts.
Targeted Therapeutics & Drug Development
Developing targeted therapies including PARP inhibitors for cervical cancer, redox-responsive polymersome drug delivery for breast cancer, and staurosporine-based anti-tumor strategies.
Computational Biology & In Silico Analysis
Applying bioinformatics, network analysis, and machine learning to GEO/TCGA data for discovering cancer biomarkers and understanding molecular mechanisms.
Cancer Biomarkers & Prognostics
Discovering and validating novel biomarkers like TRIP13, NEK2, TPX2, CTTN, MCM genes, and EMT-associated hub genes for early detection and prognosis.
Tumor Microenvironment & Metastasis
Investigating CXCL12/CXCR4 signaling, epithelial-mesenchymal transition (EMT), tumor microenvironment interactions, and immune cell infiltration in cancer progression.
Molecular Mechanisms & Signalling
Unravelling PI3K/AKT, TGF-beta, Toll-like receptor, and DNA repair pathways driving cancer progression, drug resistance, and therapeutic response.
Latest Research
View all publications
Recent Publications
2026 In Silico Research in Biomedicine
Unraveling the oncogenic and prognostic significance of CTTN gene: A comprehensive pan-cancer analysis
Bhushan R, Gupta RK, Prasad SB
DOI Link 2025 Discover Oncology
Genes associated with epithelial mesenchymal transition (EMT) in cervical cancer progression
Kumari K, Gupta RK, Kumar S et al.
DOI Link 2025 Insights and Innovations in Molecular Genetics and Cancer Biology - Taylor & Francis
Molecular Genetics Alteration and Its Prognostic Significance in Gallbladder Carcinogenesis
Gupta RK, Bhushan R, Prasad SB
DOI Link About CGTL GEO & TCGA Data Mining In Silico Network Analysis Pan-Cancer Analysis Targeted Drug Delivery
Learn More About Us
From Genes to Therapeutics
CGTL at Mahatma Gandhi Central University, Motihari focuses on understanding cancer at the molecular level — identifying key genes, pathways, and biomarkers through computational and experimental approaches.
Our work spans cervical cancer (EMT, DNA repair, cell cycle), gallbladder cancer (metabolomics, in silico biomarkers), breast cancer (targeted drug delivery), and pan-cancer analyses — translating discoveries from bench to bedside.
Genomics
DNA sequencing & analysis
Therapeutics
Drug development & testing
Computational
Bioinformatics & ML
Biomarkers
Cancer detection & diagnosis
Our Team
Meet the Researchers
Dr. Shyam Babu Prasad
Principal Investigator
Dr. Shyam has over 15 years of experience in cancer genomics research and has published more than 25 papers in high-impact journals.
Kiran Kumari
Research Scholar
Mrs. Kiran has specialization in computational analysis of cervical cancer genomics data.
Raviranjan Kumar Gupta
Research Scholar
Mr. Raviranjan Kumar Gupta is a researcher with over 3.5 years of experience in cancer bioinformatics and experimental biology. His work focuses on gallbladder cancer, molecular genetics, metabolomics, and biomarker discovery through integrative analysis of genomic and transcriptomic datasets.
Interested in Joining Our Team?
We are always looking for passionate researchers to join our laboratory at Mahatma Gandhi Central University, Motihari. Check out our open positions or contact us for more information.